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apalutamide will lower the extent or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with medications which can be CYP2C19 substrates can lead to lessen exposure to these drugs.“When the test effects arrived again, they suspected I’d h